Health Care

Painkiller Linked to Increased Risk of Major Heart Problems

Painkiller Linked to Increased Risk of Major Heart Problems

In those who took diclofenac for 30 days, the risk rose by a huge 50% - compared to those not taking any drugs.

The findings prompted researchers to say that diclofenac should not be available over the counter, and when prescribed, should be accompanied by an appropriate front package warning about its potential risks.

They said in the paper: 'Treatment of pain and inflammation with NSAIDs may be worthwhile for some patients to improve quality of life despite potential side effects.

The latest research comes a year after a decade-long Danish study found ibuprofen, commonly sold as Nurofen and Advil, had been associated with a 31 per cent increased risk of cardiac arrest.

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The researchers believe its high time that the potential health risks of the drug are recognised and that its usage is reduced, including not making it available over the counter.

Are you anxious the medication you take could be impacting your overall health negatively?

One of the most widely used painkillers may pose a threat to cardiovascular health.

Diclofenac is the most commonly used non-steroidal anti-inflammatory drug (NSAID) in low, middle, and high income countries, and it is prescribed to millions of people in the United Kingdom every year. Current concerns about the cardiovascular safety of NSAID use mean that such a trial would now be unethical, but regulators including the European Medicines Agency are still calling for the safety of diclofenac to be assessed.

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The new study, however, examined this common painkiller's negative impact on the circulatory system and found out that this drug is indeed increasing the risks of cardiovascular conditions, heart attack and stroke included, as reported by the leading author Morten Schmidt at Aarhus University Hospital in Denmark. Eligible individuals were at least 18 years of age and had at least a year of continuous prescription records before the date of the study start in 1996.

The risk of gastrointestinal bleeding at 30 days increased 4.5-fold in patients who started diclofenac compared to those who didn't. For people at high risk of cardiovascular disease, that number would shoot up to 40, with half dying.

However, researchers point out that, while the relative risk increased significantly, the overall risk was still pretty small.

More specifically, diclofenac initiators had a 50% increased rate of major cardiovascular events compared with participants who didn't take NSAIDs. Compared with taking paracetamol or ibuprofen, taking diclofenac raised cardiovascular risk by 20 percent.

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Miller had just been preparing to embark on a USA tour after releasing his most recent album, Swimming , on August 3. At the Frick Park Market, made famous in one of Miller's music videos, the day took a sudden and sad turn.

While the researchers did acknowledge this was an observational study, they also noted the sample sizes they used were larger than what has been used with previous research on the same subject.


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