Health Care

Possible blood test for Autism

Possible blood test for Autism

Autism spectrum disorders (ASD) are defined as developmental disorders mainly affecting social interaction and they can include a wide spectrum of behavioural problems.

ASD cases are characterized by a wide variety of symptoms that can range from mild behavioral issues to debilitating compulsive behavior, anxiety, cognitive impairment, and much more.

Naila Rabbaini, researcher of experimental systems biology and co-lead on the study, said that with further testing of larger number of children at younger ages, the team may be able to find new causes of autism and assess whether treatments are working.

Dr Rabbani added that she hoped the tests could also eventually reveal some of the factors that cause autism and improve its diagnosis.

"We have discovered that the energy of estimating harmed proteins to the cerebrum might be a reason for an improvement of autism", said Paul Thornalley, teacher in frameworks science at the University of Warwick, who co-drove the study.

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Their discovery was of a link between ASD and proteins in blood plasma which had been damaged by oxidation and glycation. Genetic factors have been found to account for 30-35% of cases of ASD and the remaining 65-70% can be explained by a combination environmental factors, multiple mutations, and rare genetic variants. The team believes the tests to be the first of their kind, and hope that they could help improve early detection of autism spectrum disorders (ASD).

"We also found some disturbance in the handling of the amino acid arginine which supports previous evidence of a genetic association with autism".

For this new study, published in the Molecular Autism journal, researchers looked for chemical differences in the blood and urine of 38 autistic children and 31 children without the condition, all aged between five and 12.

They created a new blood and urine test that could soon be used to diagnose autism. The AI developed a mathematical equation that distinguishes between ASD and healthy controls.

Researchers at the University of Warwick have developed two tests that could potentially detect autism in children.

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The research they have done has taken us further towards the goal of understanding and perhaps preventing children from being born with autism.

The researchers plan to duplicate the study with more children to confirm diagnostic performance and to assess whether ASD can be detected at very early stages, how likely it is to progress to more severe disease, and if treatments are effective.

Autism in children can be mild, moderate or severe, and present in so many ways that is often hard to diagnose. This study may give us clues about why autistic people are different but it does not provide a new method for diagnosis. The study also only looked at a small group of people. Speaking to the BBC, Dr. Rabbani said that the next step will be to replicate the study's findings in other groups.

"Autism can be diagnosed from the age of two but the average age of diagnosis is 4.5 years". In the United Kingdom, the number of children affected is around one in 100.

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